Proteins/UNIPROT:O15551

CLDN3

ProteinUNIPROT:O15551

Barrier-forming claudin. Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity..

Function from UniProtKB (O15551), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

30 statements

30 statements · 4 reference databases · Subject: CLDN3 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

Order

CLDN3 covaries with HDDC2ProteinHetionet hetionet:covaries:1365-51020Inferred only
CLDN3 covaries with NME3ProteinHetionet hetionet:covaries:1365-4832Inferred only
CLDN3 covaries with RORAProteinHetionet hetionet:covaries:1365-6095Inferred only
APP interacts with CLDN3ProteinHetionet hetionet:interacts:1365-351Inferred only
CLDN3 interacts with CLDN1ProteinHetionet hetionet:interacts:1365-9076Inferred only
CLDN3 interacts with CLDN5ProteinHetionet hetionet:interacts:1365-7122Inferred only
CLDN3 interacts with EGR1ProteinHetionet hetionet:interacts:1365-1958Inferred only
CLDN3 interacts with POM121ProteinHetionet hetionet:interacts:1365-9883Inferred only
CLDN3 interacts with PRKACAProteinHetionet hetionet:interacts:1365-5566Inferred only
CLDN3 interacts with TJP1ProteinHetionet hetionet:interacts:1365-7082Inferred only
CLDN3 interacts with UBCProteinHetionet hetionet:interacts:1365-7316Inferred only
CLDN3 interacts with WNK4ProteinHetionet hetionet:interacts:1365-65266Inferred only

Show the remaining 18

CLDN3 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only
CLDN3 participates in 7q11 23 copy number variation syndromePathwayWikiPathways WP4932Inferred only
CLDN3 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
CLDN3 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
CLDN3 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only
CLDN3 participates in Epithelial to mesenchymal transition in colorectal cancerPathwayWikiPathways WP4239Inferred only
CLDN3 participates in Tight junction interactionsPathwayReactome R-HSA-420029Inferred only
CLDN3 regulates negative regulation of cell migrationBiological processgene ontology O15551|GO:0030336Inferred only
CLDN3 regulates negative regulation of cell population proliferationBiological processgene ontology O15551|GO:0008285Inferred only
CLDN3 regulates negative regulation of gene expressionBiological processgene ontology O15551|GO:0010629Inferred only
CLDN3 regulates negative regulation of phosphate transmembrane transportBiological processgene ontology O15551|GO:2000186Inferred only
CLDN3 regulates positive regulation of cell migrationBiological processgene ontology O15551|GO:0030335Inferred only
CLDN3 regulates positive regulation of gene expressionBiological processgene ontology O15551|GO:0010628Inferred only
CLDN3 regulates positive regulation of wound healingBiological processgene ontology O15551|GO:0090303Inferred only
CLDN3 regulates regulation of cell morphogenesisBiological processgene ontology O15551|GO:0022604Inferred only
CLDN3 regulates regulation of membrane permeabilityBiological processgene ontology O15551|GO:0090559Inferred only
CLDN3 regulates regulation of transepithelial transportBiological processgene ontology O15551|GO:0150111Inferred only
EPRS1 decreases the expression of CLDN3ProteinHetionet hetionet:regulates:2058-1365Inferred only

Other names

7 names

Resolves to: CLDN3

Also called: C7orf1Clostridium perfringens enterotoxin receptor 2CPE-R 2CPE-receptor 2CPETR2hRVP1Rat ventral prostate.1 protein homolog

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