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Proteins/UNIPROT:O00501

CLDN5

Protein·UNIPROT:O00501

Open in the graph

Plays a major role in tight junction-specific obliteration of the intercellular space..

Function from UniProtKB (O00501), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

29 statements

29 statements · 4 reference databases · Subject: CLDN5 · Sources: gene ontology, Hetionet, Reactome, WikiPathways

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CABS1 covaries with CLDN5ProteinHetionet hetionet:covaries:7122-85438Inferred only
CLDN5 covaries with KNSTRNProteinHetionet hetionet:covaries:7122-90417Inferred only
CLDN5 covaries with SERBP1ProteinHetionet hetionet:covaries:26135-7122Inferred only
CLDN3 interacts with CLDN5ProteinHetionet hetionet:interacts:1365-7122Inferred only
CLDN5 interacts with MPDZProteinHetionet hetionet:interacts:7122-8777Inferred only
TJP1 interacts with CLDN5ProteinHetionet hetionet:interacts:7082-7122Inferred only
CLDN5 interacts with UBCProteinHetionet hetionet:interacts:7122-7316Inferred only
CLDN5 participates in 22q11 2 copy number variation syndromePathwayWikiPathways WP4657Inferred only
CLDN5 participates in 7q11 23 copy number variation syndromePathwayWikiPathways WP4932Inferred only
CLDN5 participates in Cell junction organizationPathwayReactome R-HSA-446728Inferred only
CLDN5 participates in Cell-Cell communicationPathwayReactome R-HSA-1500931Inferred only
CLDN5 participates in Cell-cell junction organizationPathwayReactome R-HSA-421270Inferred only

Show the remaining 17

CLDN5 participates in Epithelial to mesenchymal transition in colorectal cancerPathwayWikiPathways WP4239Inferred only
CLDN5 participates in Exercise induced circadian regulationPathwayWikiPathways WP410Inferred only
CLDN5 participates in Gene expression (Transcription)PathwayReactome R-HSA-74160Inferred only
CLDN5 participates in Generic Transcription PathwayPathwayReactome R-HSA-212436Inferred only
CLDN5 participates in Macrophage stimulating protein MSP signalingPathwayWikiPathways WP5353Inferred only
CLDN5 participates in RNA Polymerase II TranscriptionPathwayReactome R-HSA-73857Inferred only
CLDN5 participates in RUNX1 regulates expression of components of tight junctionsPathwayReactome R-HSA-8935964Inferred only
CLDN5 participates in Tight junction interactionsPathwayReactome R-HSA-420029Inferred only
CLDN5 participates in Transcriptional regulation by RUNX1PathwayReactome R-HSA-8878171Inferred only
CLDN5 regulates negative regulation of angiogenesisBiological processgene ontology O00501|GO:0016525Inferred only
CLDN5 regulates negative regulation of cell migrationBiological processgene ontology O00501|GO:0030336Inferred only
CLDN5 regulates negative regulation of gene expressionBiological processgene ontology O00501|GO:0010629Inferred only
CLDN5 regulates negative regulation of vascular permeabilityBiological processgene ontology O00501|GO:0043116Inferred only
CLDN5 regulates positive regulation of bicellular tight junction assemblyBiological processgene ontology O00501|GO:1903348Inferred only
CLDN5 regulates positive regulation of cell population proliferationBiological processgene ontology O00501|GO:0008284Inferred only
CLDN5 regulates positive regulation of establishment of endothelial barrierBiological processgene ontology O00501|GO:1903142Inferred only
CLDN5 regulates positive regulation of gene expressionBiological processgene ontology O00501|GO:0010628Inferred only

Other names

4 names

Resolves to: CLDN5

Also called: AWALTMDVCFTMVCFTransmembrane protein deleted in VCFS

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