Proteins/UNIPROT:Q8WUX9

CHMP7

ProteinUNIPROT:Q8WUX9

ESCRT-III-like protein required to recruit the ESCRT-III complex to the nuclear envelope (NE) during late anaphase. Together with SPAST, the ESCRT-III complex promotes NE sealing and mitotic spindle disassembly during late anaphase. Recruited to the reforming NE during anaphase by LEMD2. Plays a role in the endosomal sorting pathway..

Function from UniProtKB (Q8WUX9), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

40 statements

40 statements · 3 reference databases · Subject: CHMP7 · Sources: gene ontology, Hetionet, Reactome

Order

CHMP7 covaries with PRR7ProteinHetionet hetionet:covaries:80758-91782Inferred only
PAFAH1B3 interacts with CHMP7ProteinHetionet hetionet:interacts:5050-91782Inferred only
UBC interacts with CHMP7ProteinHetionet hetionet:interacts:7316-91782Inferred only
USP8 interacts with CHMP7ProteinHetionet hetionet:interacts:9101-91782Inferred only
CHMP7 participates in AutophagyPathwayReactome R-HSA-9612973Inferred only
CHMP7 participates in Budding and maturation of HIV virionPathwayReactome R-HSA-162588Inferred only
CHMP7 participates in Cell CyclePathwayReactome R-HSA-1640170Inferred only
CHMP7 participates in Cell Cycle, MitoticPathwayReactome R-HSA-69278Inferred only
CHMP7 participates in DiseasePathwayReactome R-HSA-1643685Inferred only
CHMP7 participates in Early SARS-CoV-2 Infection EventsPathwayReactome R-HSA-9772572Inferred only
CHMP7 participates in Endosomal Sorting Complex Required For Transport (ESCRT)PathwayReactome R-HSA-917729Inferred only
CHMP7 participates in HCMV InfectionPathwayReactome R-HSA-9609646Inferred only

Show the remaining 28

CHMP7 participates in HCMV Late EventsPathwayReactome R-HSA-9610379Inferred only
CHMP7 participates in HIV InfectionPathwayReactome R-HSA-162906Inferred only
CHMP7 participates in HIV Life CyclePathwayReactome R-HSA-162587Inferred only
CHMP7 participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
CHMP7 participates in Late endosomal microautophagyPathwayReactome R-HSA-9615710Inferred only
CHMP7 participates in Late Phase of HIV Life CyclePathwayReactome R-HSA-162599Inferred only
CHMP7 participates in M PhasePathwayReactome R-HSA-68886Inferred only
CHMP7 participates in MacroautophagyPathwayReactome R-HSA-1632852Inferred only
CHMP7 participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
CHMP7 participates in Mitotic AnaphasePathwayReactome R-HSA-68882Inferred only
CHMP7 participates in Mitotic Metaphase and AnaphasePathwayReactome R-HSA-2555396Inferred only
CHMP7 participates in Nuclear Envelope (NE) ReassemblyPathwayReactome R-HSA-2995410Inferred only
CHMP7 participates in Programmed Cell DeathPathwayReactome R-HSA-5357801Inferred only
CHMP7 participates in PyroptosisPathwayReactome R-HSA-5620971Inferred only
CHMP7 participates in Regulated NecrosisPathwayReactome R-HSA-5218859Inferred only
CHMP7 participates in SARS-CoV InfectionsPathwayReactome R-HSA-9679506Inferred only
CHMP7 participates in SARS-CoV-1 InfectionPathwayReactome R-HSA-9678108Inferred only
CHMP7 participates in SARS-CoV-2 InfectionPathwayReactome R-HSA-9694516Inferred only
CHMP7 participates in Sealing of the nuclear envelope (NE) by ESCRT-IIIPathwayReactome R-HSA-9668328Inferred only
CHMP7 participates in Translation of Replicase and Assembly of the Replication Transcription ComplexPathwayReactome R-HSA-9694676Inferred only
CHMP7 participates in Translation of Replicase and Assembly of the Replication Transcription ComplexPathwayReactome R-HSA-9679504Inferred only
CHMP7 participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
CHMP7 participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
CHMP7 regulates regulation of mitotic spindle assemblyBiological processgene ontology Q8WUX9|GO:1901673Inferred only
FADS1 decreases the expression of CHMP7ProteinHetionet hetionet:regulates:3992-91782Inferred only
GTF2E2 decreases the expression of CHMP7ProteinHetionet hetionet:regulates:2961-91782Inferred only
NOSIP decreases the expression of CHMP7ProteinHetionet hetionet:regulates:51070-91782Inferred only
VRK1 decreases the expression of CHMP7ProteinHetionet hetionet:regulates:7443-91782Inferred only

Other names

2 names

Resolves to: CHMP7

Also called: Charged multivesicular body protein 7Chromatin-modifying protein 7

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