Loading the page.
Proteins/UNIPROT:Q9BZP6
Degrades chitin and chitotriose. May participate in the defense against nematodes, fungi and other pathogens. Plays a role in T-helper cell type 2 (Th2) immune response. Contributes to the response to IL-13 and inflammation in response to IL-13. Stimulates chemokine production by pulmonary epithelial cells. Protects lung epithelial cells against apoptosis and promotes phosphorylation of AKT1. Its function in the inflammatory response and in protecting cells against apoptosis is inhibited by allosamidin, suggesting that the function of this protein depends on carbohydrate binding..
Function from UniProtKB (Q9BZP6), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
21 statements
21 statements · 3 reference databases · Subject: CHIA · Sources: gene ontology, Hetionet, Reactome
4 reactions
2MAM01438e+waterN,N'-diacetylchitobiose
Reaction pageLeft to rightBalancedEC 3.2.1.14extracellular space
Human-GEM MAR03986CC BY 4.0Reference data
MAM01438c+waterN-acetyl-D-glucosamine
Catalysed by MANSC1 or CHIT1 or CHIA
Reaction pageLeft to rightBalancedEC 3.2.1.14cytosol
2 names
Resolves to: CHIA
MAM01438e+waterN-acetyl-D-glucosamine
Catalysed by CHIA
Reaction pageLeft to rightBalancedEC 3.2.1.14extracellular space
Human-GEM MAR08376CC BY 4.0Reference data
MAM01437c+waterMAM01436c+N-acetyl-D-glucosamine
Catalysed by MANSC1 or CHIT1 or CHIA
Reaction pageLeft to rightBalancedEC 3.2.1.14cytosol
Human-GEM MAR09485CC BY 4.0Reference data