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A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:Q13231

CHIT1

Protein·UNIPROT:Q13231

Open in the graph

Degrades chitin, chitotriose and chitobiose. May participate in the defense against nematodes and other pathogens. Isoform 3 has no enzymatic activity..

Function from UniProtKB (Q13231), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

7 statements

7 statements · 2 reference databases · Subject: CHIT1 · Sources: Hetionet, Reactome

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CHIT1 interacts with ELANEProteinHetionet hetionet:interacts:1118-1991Inferred only
CHIT1 participates in DigestionPathwayReactome R-HSA-8935690Inferred only
CHIT1 participates in Digestion and absorptionPathwayReactome R-HSA-8963743Inferred only
CHIT1 participates in Digestion of dietary carbohydratePathwayReactome R-HSA-189085Inferred only
CHIT1 participates in Immune SystemPathwayReactome R-HSA-168256Inferred only
CHIT1 participates in Innate Immune SystemPathwayReactome R-HSA-168249Inferred only
CHIT1 participates in Neutrophil degranulationPathwayReactome R-HSA-6798695Inferred only

Reactions

3 reactions

2MAM01438e+waterN,N'-diacetylchitobiose
Catalysed by CHIT1 or CHIA
Reaction pageLeft to rightBalancedEC 3.2.1.14extracellular space
Human-GEM MAR03986CC BY 4.0Reference data
MAM01438c+waterN-acetyl-D-glucosamine
Catalysed by MANSC1 or CHIT1 or CHIA
Reaction pageLeft to rightBalancedEC 3.2.1.14cytosol

Other names

1 name

Resolves to: CHIT1

Also called: Chitinase-1

← Every protein Find it in the graph →

Human-GEM MAR08375

CC BY 4.0

Reference data

MAM01437c+waterMAM01436c+N-acetyl-D-glucosamine

Catalysed by MANSC1 or CHIT1 or CHIA

Reaction pageLeft to rightBalancedEC 3.2.1.14cytosol

Human-GEM MAR09485CC BY 4.0Reference data