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Proteins/UNIPROT:Q15878
Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells. They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents. R-type calcium channels belong to the 'high-voltage activated' (HVA) group and are blocked by nickel. They are however insensitive to dihydropyridines (DHP). Calcium channels containing alpha-1E subunit could be involved in the modulation of firing patterns of neurons which is important for information processing..
[Isoform 3]: Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells. They are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death. The isoform alpha-1E gives rise to R-type calcium currents..
Function from UniProtKB (Q15878), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
3 rows
14 statements
14 statements · 4 reference databases · Subject: CACNA1E · Sources: Hetionet, Reactome, Rhea, WikiPathways
1 reaction
6 names
Resolves to: CACNA1E