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Proteins/UNIPROT:O94823
Catalytic component of a P4-ATPase flippase complex, which catalyzes the hydrolysis of ATP coupled to the transport of glucosylceramide (GlcCer) from the outer to the inner leaflet of lysosome membranes. Plays an important role in the maintenance of lysosome membrane integrity and function in cortical neurons..
Function from UniProtKB (O94823), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
14 statements
14 statements · 5 reference databases · Subject: ATP10B · Sources: Bgee, Hetionet, Reactome, Rhea, UniProt
1 reaction
a beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine+ATP(4-)+watera beta-D-glucosyl-(1<->1')-N-acylsphing-4-enine+ADP(3-)+hydrogenphosphate+hydron
Transported by ATP10A or ATP10B or ATP10D
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:66036CC BY 4.0Reference data
4 names
Resolves to: ATP10B