Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Chemistry

ReactionsRhea and Human-GEM, by subsystem
ReachWhat a compound can become

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed
DiseasesFeatures, genes, and where each sits

Atlas Graph Twin Access

Search the graph

Reference

Evidence

Compounds
Outcomes
Proteins
Interactions
Papers
Articles

Chemistry

Reactions
Reach

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases

Atlas Graph Twin Access

Loading the page.

Catalyst

Computational infrastructure for human biology, built on a provenance-aware knowledge graph. Findings retain their sources; research and simulation are the next layers.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments
Diseases
Reactions
Reach

How it works

Mission
Method
Twin
How to read the evidence
Sources and licences

Build on it

Access
In your assistant
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Proteins/UNIPROT:A6NI28

ARHGAP42

Protein·UNIPROT:A6NI28

Open in the graph

May influence blood pressure by functioning as a GTPase-activating protein for RHOA in vascular smooth muscle..

Function from UniProtKB (A6NI28), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

Statements

10 statements

10 statements · 2 reference databases · Subject: ARHGAP42 · Sources: Hetionet, Reactome

Search this listOrder

ARHGAP42 covaries with SESN3ProteinHetionet hetionet:covaries:143686-143872Inferred only
ARHGAP42 participates in CDC42 GTPase cyclePathwayReactome R-HSA-9013148Inferred only
ARHGAP42 participates in RAC1 GTPase cyclePathwayReactome R-HSA-9013149Inferred only
ARHGAP42 participates in RAC2 GTPase cyclePathwayReactome R-HSA-9013404Inferred only
ARHGAP42 participates in RAC3 GTPase cyclePathwayReactome R-HSA-9013423Inferred only
ARHGAP42 participates in RHO GTPase cyclePathwayReactome R-HSA-9012999Inferred only
ARHGAP42 participates in RHOA GTPase cyclePathwayReactome R-HSA-8980692Inferred only
ARHGAP42 participates in Signal TransductionPathwayReactome R-HSA-162582Inferred only
ARHGAP42 participates in Signaling by Rho GTPasesPathwayReactome R-HSA-194315Inferred only
ARHGAP42 participates in Signaling by Rho GTPases, Miro GTPases and RHOBTB3PathwayReactome R-HSA-9716542Inferred only

Other names

4 names

Resolves to: ARHGAP42

Also called: GRAF3Rho GTPase-activating protein 10-likeRho-type GTPase-activating protein 42TMEM133

← Every protein Find it in the graph →