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Proteins/UNIPROT:Q8N7J2
Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex..
Function from UniProtKB (Q8N7J2), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
15 statements
15 statements · 2 reference databases · Subject: AMER2 · Sources: gene ontology, Hetionet
2 names
Resolves to: AMER2