Loading the page.
Proteins/UNIPROT:O14678
Lysosomal membrane protein that transports cobalamin (Vitamin B12) from the lysosomal lumen to the cytosol in an ATP-dependent manner. Targeted by LMBRD1 lysosomal chaperone from the endoplasmic reticulum to the lysosomal membrane. Then forms a complex with lysosomal chaperone LMBRD1 and cytosolic MMACHC to transport cobalamin across the lysosomal membrane..
Function from UniProtKB (O14678), read 2026-09-23. CC BY 4.0.
Curated compounds routed: 0
1 row
26 statements
26 statements · 3 reference databases · Subject: ABCD4 · Sources: Hetionet, Reactome, Rhea
1 reaction
an R-cob(III)alamin+ATP(4-)+wateran R-cob(III)alamin+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCD4
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:17873CC BY 4.0Reference data
8 names
Resolves to: ABCD4