Transport of RCbl within the body

The steps of transport of cobalamins (RCbl) from the enterocyte to the cells in which it will function as a cofactor, together with its reuptake in the renal tubule, are annotated here. While methylcobalamin is the predominant cobalamin in the blood, other cobalamins including cyanocobalamin and adenosylcobalamin are also present and the proteins involved in these processes accommodate all of them. This broad specificity is indicated by annotating R-cob(III)alamin (RCbl - CHEBI:140785) as the cargo in all of these processes.

Summary from Reactome (R-HSA-9758890), read 2026-09-23.