Pathway
The fatty acid cycling model
The "fatty acid cycling" hypothesis proposes that protonated fatty acids flip-flop in the membrane and deliver a proton to the matrix side. UCP1 catalyses the return of the fatty acid anion to the cytosolic side of the membrane, resulting in net proton transport catalysed by the protein.
REACT:R-HSA-167826Reactome
What the reference databases state
Statements
5 statements
5 statements · 1 reference database · Subject: The fatty acid cycling model · Sources: Reactome
- SLC25A14 participates in The fatty acid cycling modelProteinReactome R-HSA-167826Inferred only
- SLC25A27 participates in The fatty acid cycling modelProteinReactome R-HSA-167826Inferred only
- UCP1 participates in The fatty acid cycling modelProteinReactome R-HSA-167826Inferred only
- UCP2 participates in The fatty acid cycling modelProteinReactome R-HSA-167826Inferred only
- UCP3 participates in The fatty acid cycling modelProteinReactome R-HSA-167826Inferred only