Pathway
Tgif disruption of Shh signaling
Mutations in the Sonic Hedgehog (SHH) gene result in HPE in humans and mice, and the Shh pathway is targeted by other mutations that cause holoprosencephaly (HPE). HPE is a severe human genetic dis...
WP:3674
What the reference databases state
Statements
9 statements
9 statements · 1 reference database · Subject: Tgif disruption of Shh signaling · Sources: WikiPathways
- FGF8 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- FOXG1 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- GLI3 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- NKX2-1 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- NODAL participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- SHH participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- SMAD2 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- TGIF1 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only
- TGIF2 participates in Tgif disruption of Shh signalingProteinWikiPathways WP3674Inferred only