Pathway
Regulation of necroptotic cell death
A regulated balance between cell survival and cell death is essential for normal development and homeostasis of multicellular organisms. Defects in control of this balance may contribute to autoimmune disease, neurodegeneration, ischemia/reperfusion injury, non alcoholic steatohepatitis (NASH) and cancer.
REACT:R-HSA-5675482Reactome
What the reference databases state
Statements
31 statements
31 statements · 1 reference database · Subject: Regulation of necroptotic cell death · Sources: Reactome
- BIRC2 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- BIRC3 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- CASP8 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- CDC37 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- FADD participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- FAS participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- FASLG participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- FLOT1 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- FLOT2 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- HSP90AA1 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- ITCH participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- MLKL participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
Show the remaining 19
- OGT participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- PDCD6IP participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- PELI1 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- PRKN participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- RIPK1 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- RIPK3 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- RPS27A participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- SDCBP participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- STUB1 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- TNFRSF10A participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- TNFRSF10B participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- TNFSF10 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- TRADD participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- TRAF2 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- UBA52 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- UBB participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- UBC participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- UBE2L3 participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only
- XIAP participates in Regulation of necroptotic cell deathProteinReactome R-HSA-5675482Inferred only