Pathway

Metabolism of ingested SeMet, Sec, MeSec into H2Se

Inorganic (selenite, SeO3(2-); and selenate, SeO4(2-)) and organic (selenocysteine, Sec; and selenomethionine, SeMet) forms of selenium can introduced in the diet where they are transformed into the intermediate selenide (Se(2-)) through the trans-selenation pathway, selenocysteine lyase (SCLY), and cystathionine gamma-lyase (CTH).

Summary from Reactome (R-HSA-2408508), read 2026-09-23.

REACT:R-HSA-2408508Reactome

Open in the graph

What the reference databases state

Statements

8 statements

8 statements · 1 reference database · Subject: Metabolism of ingested SeMet, Sec, MeSec into H2Se · Sources: Reactome

Order

AHCY participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
CBS participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
CTH participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
GNMT participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
HNMT participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
MAT1A participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
NNMT participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only
SCLY participates in Metabolism of ingested SeMet, Sec, MeSec into H2SeProteinReactome R-HSA-2408508Inferred only