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Proteins/UNIPROT:Q8NEZ2

VPS37A

Protein·UNIPROT:Q8NEZ2

Open in the graph

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies. May be involved in cell growth and differentiation..

Function from UniProtKB (Q8NEZ2), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

1 row

hereditary spastic paraplegia 53 has a germline basis in VPS37ADiseaseGenCC HGNC:24928|MONDO:0013962Inferred only

Statements

25 statements

25 statements · 3 reference databases · Subject: VPS37A · Sources: Hetionet, Reactome, WikiPathways

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VPS37A covaries with MYBPHLProteinHetionet hetionet:covaries:137492-343263Inferred only
VPS37A covaries with STACProteinHetionet hetionet:covaries:137492-6769Inferred only
APP interacts with VPS37AProteinHetionet hetionet:interacts:137492-351Inferred only
HGS interacts with VPS37AProteinHetionet hetionet:interacts:137492-9146Inferred only
TSG101 interacts with VPS37AProteinHetionet hetionet:interacts:137492-7251Inferred only
UBC interacts with VPS37AProteinHetionet hetionet:interacts:137492-7316Inferred only
VPS28 interacts with VPS37AProteinHetionet hetionet:interacts:137492-51160Inferred only
VPS37A participates in 7q11 23 copy number variation syndromePathwayWikiPathways WP4932Inferred only
VPS37A participates in Assembly Of The HIV VirionPathwayReactome R-HSA-175474Inferred only
VPS37A participates in AutophagyPathwayReactome R-HSA-9612973Inferred only
VPS37A participates in Budding and maturation of HIV virionPathwayReactome R-HSA-162588Inferred only
VPS37A participates in DiseasePathwayReactome R-HSA-1643685Inferred only

Show the remaining 13

VPS37A participates in Endosomal Sorting Complex Required For Transport (ESCRT)PathwayReactome R-HSA-917729Inferred only
VPS37A participates in HCMV InfectionPathwayReactome R-HSA-9609646Inferred only
VPS37A participates in HCMV Late EventsPathwayReactome R-HSA-9610379Inferred only
VPS37A participates in HIV InfectionPathwayReactome R-HSA-162906Inferred only
VPS37A participates in HIV Life CyclePathwayReactome R-HSA-162587Inferred only
VPS37A participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only
VPS37A participates in Late endosomal microautophagyPathwayReactome R-HSA-9615710Inferred only
VPS37A participates in Late Phase of HIV Life CyclePathwayReactome R-HSA-162599Inferred only
VPS37A participates in Membrane binding and targetting of GAG proteinsPathwayReactome R-HSA-174490Inferred only
VPS37A participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
VPS37A participates in Synthesis And Processing Of GAG, GAGPOL PolyproteinsPathwayReactome R-HSA-174495Inferred only
VPS37A participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
VPS37A participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only

Other names

4 names

Resolves to: VPS37A

Also called: ESCRT-I complex subunit VPS37AHCRP1Hepatocellular carcinoma-related protein 1hVps37A

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