Proteins/UNIPROT:Q9H7P6

MVB12B

ProteinUNIPROT:Q9H7P6

Component of the ESCRT-I complex, a regulator of vesicular trafficking process. Required for the sorting of endocytic ubiquitinated cargos into multivesicular bodies.

Function from UniProtKB (Q9H7P6), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Statements

28 statements

28 statements · 3 reference databases · Subject: MVB12B · Sources: gene ontology, Hetionet, Reactome

Order

MVB12B covaries with ANAPC1ProteinHetionet hetionet:covaries:64682-89853Inferred only
UBC interacts with MVB12BProteinHetionet hetionet:interacts:7316-89853Inferred only
MVB12B participates in Assembly Of The HIV VirionPathwayReactome R-HSA-175474Inferred only
MVB12B participates in AutophagyPathwayReactome R-HSA-9612973Inferred only
MVB12B participates in Budding and maturation of HIV virionPathwayReactome R-HSA-162588Inferred only
MVB12B participates in DiseasePathwayReactome R-HSA-1643685Inferred only
MVB12B participates in Endosomal Sorting Complex Required For Transport (ESCRT)PathwayReactome R-HSA-917729Inferred only
MVB12B participates in HCMV InfectionPathwayReactome R-HSA-9609646Inferred only
MVB12B participates in HCMV Late EventsPathwayReactome R-HSA-9610379Inferred only
MVB12B participates in HIV InfectionPathwayReactome R-HSA-162906Inferred only
MVB12B participates in HIV Life CyclePathwayReactome R-HSA-162587Inferred only
MVB12B participates in Infectious diseasePathwayReactome R-HSA-5663205Inferred only

Show the remaining 16

MVB12B participates in Late endosomal microautophagyPathwayReactome R-HSA-9615710Inferred only
MVB12B participates in Late Phase of HIV Life CyclePathwayReactome R-HSA-162599Inferred only
MVB12B participates in Membrane binding and targetting of GAG proteinsPathwayReactome R-HSA-174490Inferred only
MVB12B participates in Membrane TraffickingPathwayReactome R-HSA-199991Inferred only
MVB12B participates in Synthesis And Processing Of GAG, GAGPOL PolyproteinsPathwayReactome R-HSA-174495Inferred only
MVB12B participates in Vesicle-mediated transportPathwayReactome R-HSA-5653656Inferred only
MVB12B participates in Viral Infection PathwaysPathwayReactome R-HSA-9824446Inferred only
MVB12B regulates regulation of epidermal growth factor receptor signaling pathwayBiological processgene ontology Q9H7P6|GO:0042058Inferred only
ACO2 increases the expression of MVB12BProteinHetionet hetionet:regulates:50-89853Inferred only
BCL2 increases the expression of MVB12BProteinHetionet hetionet:regulates:596-89853Inferred only
CASP3 increases the expression of MVB12BProteinHetionet hetionet:regulates:836-89853Inferred only
ENTPD6 increases the expression of MVB12BProteinHetionet hetionet:regulates:955-89853Inferred only
PPOX increases the expression of MVB12BProteinHetionet hetionet:regulates:5498-89853Inferred only
RXRA increases the expression of MVB12BProteinHetionet hetionet:regulates:6256-89853Inferred only
SOX2 increases the expression of MVB12BProteinHetionet hetionet:regulates:6657-89853Inferred only
STK39 increases the expression of MVB12BProteinHetionet hetionet:regulates:27347-89853Inferred only

Other names

4 names

Resolves to: MVB12B

Also called: C9orf28ESCRT-I complex subunit MVB12BFAM125BProtein FAM125B

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