Pathway
Conjugation of benzoate with glycine
Benzoic acid, widely used as a food preservative, is converted to hippuric acid by activation and conjugation with glycine. This was one of the first detoxification pathways discovered, and was formerly exploited clinically as an alternative means of nitrogen excretion in patients with urea cycle defects.
REACT:R-HSA-177135Reactome
What the reference databases state
Statements
6 statements
6 statements · 1 reference database · Subject: Conjugation of benzoate with glycine · Sources: Reactome
- ACSM1 participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only
- ACSM2B participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only
- GLYAT participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only
- GLYATL1 participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only
- GLYATL2 participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only
- GLYATL3 participates in Conjugation of benzoate with glycineProteinReactome R-HSA-177135Inferred only