(11Z,14Z)-eicosadienoyl-CoA

Three steps

• N-docosanoylglycineReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. long-chain-fatty-acid-CoA ligase (behenic acid)
  3. docosanoyl-CoA + glycine = N-docosanoylglycine + CoA + H(+)

  Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosolOne of 2 routes

• N-hexacosanoylglycineReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. long-chain-fatty-acid-CoA ligase (cerotic acid)
  3. hexacosanoyl-CoA + glycine = N-hexacosanoylglycine + CoA + H(+)

  Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 7 morecytosolOne of 2 routes

• (2E,5Z)-tetradecadienoyl-CoAReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. long-chain-fatty-acid-CoA ligase (physeteric acid)
  3. medium-chain acyl-CoA dehydrogenase (5-tetradecenoyl-CoA)

  Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 4 routes

• (2E,7Z)-hexadecadienoyl-CoAReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. long-chain-fatty-acid-CoA ligase (7-palmitoleic acid)
  3. medium-chain acyl-CoA dehydrogenase (7-hexadecenoyl-CoA)

  Catalysed by BAAT, ACOT6, ACOT1, SLC27A2 and 11 morecytosol, mitochondrial matrixOne of 4 routes

• cholesteryl (11Z)-octadecenoateReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. Transport of 11-Octadecenoyl Carnitine into the Mitochondrial Matrix
  3. (11Z)-octadecenoyl-CoA + cholesterol = cholesteryl (11Z)-octadecenoate + CoA

  Catalysed by BAAT, ACOT6, ACOT1, CPT1A and 3 morecytosol

• taurochenodeoxycholateReach from here →
  1. (11Z,14Z)-eicosadienoyl-CoA hydrolase
  2. Propanoyl-CoA:acetyl-CoA C-acyltransferase
  3. 3alpha,7alpha-dihydroxy-5beta-cholanoyl-CoA:taurine N-choloyltransferase

  Catalysed by BAAT, ACOT6, ACOT1, ACAA1 and 2 morecytosol, peroxisomeOne of 5 routes