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Catalyst

sodium chlorideFinding

Sodium chloride increases systolic blood pressure (setting unspecified)

raisesVery limited evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“In double blind crossover study mean supine systolic blood pressure rose significantly (p less than 0.005) during sodium supplementation (to 171 mm Hg) compared with value after three months of sodium restriction alone (159.9 mm Hg) and after one month of placebo (161.8 mm Hg).”
Quoted verbatim from Sodium restriction and blood pressure in hypertensive type II diabetics: randomised blind controlled and crossover studies of moderate sodium restriction and sodium supplementation.
This finding among the 88 findings on its endpoint

sodium chloride

Systolic blood pressure (setting unspecified)

raises

Who
Nine patients with type II diabetes and mild hypertension in the crossover phase, all continuing moderate dietary sodium restriction in both periods, some on antihypertensive agents other than diuretics; supine blood pressure
Dose studied
Slow Sodium (sustained release sodium preparation) 80 mmol daily for one month versus matching placebo for one month

Very limited evidencePMID 2493869 · 1989

02 · The study

Study
crossover
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

BMJ (Clinical research ed.)
What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M71F0BGXG6KSBS7ESNZJE5Z9