PapersPMID:2493869
Sodium restriction and blood pressure in hypertensive type II diabetics: randomised blind controlled and crossover studies of moderate sodium restriction and sodium supplementation.
What moved
1 findingHow to read these marks →- Increases systolic blood pressure
very limited
“In double blind crossover study mean supine systolic blood pressure rose significantly (p less than 0.005) during sodium supplementation (to 171 mm Hg) compared with value after three months of sodium restriction alone (159.9 mm Hg) and after one month of placebo (161.8 mm Hg).”
- Study
- crossover
- Dose studied
- Slow Sodium (sustained release sodium preparation) 80 mmol daily for one month versus matching placebo for one month
- Population
- Nine patients with type II diabetes and mild hypertension in the crossover phase, all continuing moderate dietary sodium restriction in both periods, some on antihypertensive agents other than diuretics; supine blood pressure
Study record
- Design
- crossover trial / randomised controlled trial
- Species
- human
- Population
- Type II diabetics with mild hypertension, diabetic outpatient clinic; crossover phase in nine patients continuing moderate sodium restriction
- Participants
- 34
- Comparator
- placebo
- Duration
- 91 days
- Endpoints measured
- 8