N-hexadecanoylethanolamine has no detected effect on lean body mass

no difference foundModerate evidenceFinding

01 · The sentence it was drawn from

“Lean mass increased by 2.0 ± 2.0% and 2.4 ± 2.1% in the PEA and PLA groups respectively, with no significant differences between groups (ITT: p = 0.38; PP: p = 0.39; Table 2; Fig. 3C).”

Quoted verbatim from The Effect of Palmitoylethanolamide (PEA) on Skeletal Muscle Hypertrophy, Strength, and Power in Response to Resistance Training in Healthy Active Adults: A Double-Blind Randomized Control Trial.

This finding among the 14 findings on its endpoint

N-hexadecanoylethanolamine

Lean body mass

no difference found

Who: n = 48 · Healthy, untrained, recreationally active adults aged 18-35 y; both arms did the same supervised 8-week resistance training programme with a standardised pre-workout snack and a post-session protein beverage; placebo was maltodextrin; intention-to-treat analysis
Dose studied: Levagen+ 175 mg capsule (not less than 150 mg PEA) twice daily, oral, 8 weeks

Moderate evidencePMID 38844675 · 2024

02 · The study

Study: RCT
Participants: 48
Duration: 8 weeks

Evidence, by strength

strong
moderatethis finding
limited
very limited
insufficient

03 · The paper

Sports medicine - open

The Effect of Palmitoylethanolamide (PEA) on Skeletal Muscle Hypertrophy, Strength, and Power in Response to Resistance Training in Healthy Active Adults: A Double-Blind Randomized Control Trial.

2024PMID 38844675doi 10.1186/s40798-024-00732-6Industry funded

What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M70G356538177RJ73JVBEJZM