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sodium chlorideFinding

Sodium chloride decreases plasma nitrate concentration

lowersLimited evidenceFinding

01 · The sentence it was drawn from

“Plasma nitrate was significantly lower following high sodium intake compared with low sodium intake (p = 0.019).”

Quoted verbatim from Effect of sodium balance on levels of nitrates in healthy subjects: Posthoc analysis of a randomized, double-blinded, placebo-controlled, crossover study.

This finding among the 10 findings on its endpoint

sodium chloride

Plasma nitrate concentration

lowers

Who: 27 healthy adults (14 men, 13 women; age 27 ± 7 years) in a randomised, double-blinded crossover study; both periods followed a standardised diet of about 100 mmol sodium per day for 4 days, with sodium chloride capsules in one period and a potato-starch and lactose placebo in the other; fasting morning sample on the examination day
Dose studied: 200 mmol sodium per day as sodium chloride enterotablets in 16 gelatin capsules, taken three times daily for 4 days

Limited evidencePMID 40827100 · 2025

02 · The study

Study: crossover
Duration: 4 days

Evidence, by strength

strong
moderate
limitedthis finding
very limited
insufficient

03 · The paper

Physiological reports

Effect of sodium balance on levels of nitrates in healthy subjects: Posthoc analysis of a randomized, double-blinded, placebo-controlled, crossover study.

2025PMID 40827100doi 10.14814/phy2.70512

What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6ZWN4MT5ZWC0MMYN71N63JK