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Catalyst

CollagenFinding

Collagen decreases serum leptin

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“Four studies (64 rodents) investigating adipokines (leptin and adiponectin) showed significant differences following CP supplementation for adiponectin (increased, p < 0.01; SMD = 1.04; CI = 0.47, 1.6) and leptin (decreased, p = 0.01; SMD = −1.33; CI = −2.36, −0.31; both Fig. 4B, C, respectively).”
Quoted verbatim from Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents-a systematic review with meta-analysis of animal trials.
This finding among the 24 findings on its endpoint

Collagen

Serum leptin

lowers

Effect as reported

−1.33standardised mean difference

CI −2.36 to −0.31

Who
n = 64 · Genetically unmodified mice and rats on a high-fat or high-caloric diet in both arms; pooled estimate from the highest collagen peptide dose of each trial
Dose studied
not reported

Very limited evidencePMID 41168365 · 2026

02 · The study

Study
animal · not in humans
Participants
64
Duration
not reported

Evidence, by strength

  • strong
  • moderate
  • limited
  • very limitedthis finding
  • insufficient

03 · The paper

International journal of obesity (2005)
What else it reported7 findings · 1 compound · 7 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5VFYTDKMCEWJYWF186HMH