Collagen has no detected effect on total cholesterol (TC)

no difference foundVery limited evidenceFinding

01 · The sentence it was drawn from

“Twelve studies comprising 188 rodents investigating total cholesterol reported no significant differences between control and CP group (p = 0.08; SMD = −1.49; CI = −3.17, 0.18).”

Quoted verbatim from Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents-a systematic review with meta-analysis of animal trials.

This finding among the 116 findings on its endpoint

Collagen

Total cholesterol (TC)

no difference found

Effect as reported

−1.49standardised mean difference

CI −3.17 to 0.18

Who: n = 188 · Genetically unmodified mice and rats on a high-fat or high-caloric diet in both arms; pooled estimate from the highest collagen peptide dose of each trial
Dose studied: not reported

Very limited evidencePMID 41168365 · 2026

02 · The study

Study: animal · not in humans
Participants: 188
Duration: not reported

Evidence, by strength

strong
moderate
limited
very limitedthis finding
insufficient

03 · The paper

International journal of obesity (2005)

Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents-a systematic review with meta-analysis of animal trials.

2026PMID 41168365doi 10.1038/s41366-025-01905-3

What else it reported7 findings · 1 compound · 7 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5VF2EG9Z84D2Y6YNWWTK3