Collagen decreases LDL cholesterol

lowersVery limited evidenceFinding

01 · The sentence it was drawn from

“Seven trials measuring LDL levels in 118 rodents resulted in a significantly lower LDL amount following prolonged CP administration (p < 0.01; SMD = −2.02; CI = −3.15, −0.88).”

Quoted verbatim from Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents-a systematic review with meta-analysis of animal trials.

This finding among the 103 findings on its endpoint

Collagen

LDL cholesterol

lowers

Effect as reported

−2.02standardised mean difference

CI −3.15 to −0.88

Who: n = 118 · Genetically unmodified mice and rats on a high-fat or high-caloric diet in both arms; pooled estimate from the highest collagen peptide dose of each trial
Dose studied: not reported

Very limited evidencePMID 41168365 · 2026

02 · The study

Study: animal · not in humans
Participants: 118
Duration: not reported

Evidence, by strength

strong
moderate
limited
very limitedthis finding
insufficient

03 · The paper

International journal of obesity (2005)

Regular collagen peptide administration exerts anti-obesity effects in high-caloric diet-fed rodents-a systematic review with meta-analysis of animal trials.

2026PMID 41168365doi 10.1038/s41366-025-01905-3

What else it reported7 findings · 1 compound · 7 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y5VDS88X5CVGXWBEK88TWT