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magnesium(2+)Finding

Magnesium(2+) increases time to first postoperative analgesic request

raisesModerate evidenceFindingreplicated ×1

01 · The sentence it was drawn from

“As shown in Fig. 6, IA Mg was associated with significantly prolonging of the time to analgesic requirement (MD = 329.99, 95% CI: 228.73–431.24; p < 0.00001; I2 = 99%) (Table 2).”
Quoted verbatim from Intra-articular magnesium to alleviate postoperative pain after arthroscopic knee surgery: a meta-analysis of randomized controlled trials.
This finding among the 3 findings on its endpoint

magnesium(2+)

Time to first postoperative analgesic request

raises

Effect as reported

329.99mean difference

CI 228.73 to 431.24

Who
Adults after arthroscopic knee surgery; eleven pooled randomised trials of intra-articular magnesium (alone or with a local anaesthetic) against saline or the same local anaesthetic alone; time to first analgesic request in minutes
Dose studied
intra-articular magnesium, per-trial doses from 0.15 g to 1.5 g in 10 to 30 mL (one trial 10 mg/kg)

Moderate evidencePMID 33546717 · 2021

02 · The study

Study
meta-analysis
Duration
not reported

Evidence, by strength

  • strong
  • moderatethis finding
  • limited
  • very limited
  • insufficient

03 · The paper

Journal of orthopaedic surgery and research
What else it reported2 findings · 1 compound · 2 endpoints

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M6Y3CXN0N4VNSM0979C1HE25