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melatonin/Finding

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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.

  • melatonin — no detected effect on interleukin-6 concentration

    Evidence strength: very limited.FindingNull result
    “These results suggest a proinflammatory action, but there were no significant effects of melatonin treatment on clinical assessments of patient symptoms or the concentrations of three proinflammatory cytokines, IL-1beta, IL-6 and TNF-alpha.”
    Quoted verbatim from Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin..
    Study
    RCT
    Duration
    6 months
    Dose
    10 mg melatonin at night
    Population
    Adults with rheumatoid arthritis on ongoing medication in both arms, monthly samples over 6 months

    Inflammatory status and kynurenine metabolism in rheumatoid arthritis treated with melatonin.2007PMID:1750678110.1111/j.1365-2125.2007.02911.xPermalink

To cite this finding: https://catalystproject.ai/e/01M5RZ69B85BBR3ZR29R4ZFB0D

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