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Berberis vulgaris/Finding

One finding, on its own

A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.

  • Berberis vulgaris — no detected effect on glycated haemoglobin (HbA1c)

    Evidence strength: moderate.FindingNull result
    “Barberry supplementation showed a significant effect on FBS (WMD = − 16.69 mg/dL; 95% CI: − 30.46 to − 2.93; p = 0.017; I2 = 96.6%; p < 0.001), HOMA-IR (WMD = − 0.95; 95% CI: − 1.79 to − 0.12; p = 0.025; I2 = 89.1%; p < 0.001), insulin (WMD = − 1.70 mU/L; 95% CI: − 2.33 to − 1.08; p < 0.001; I2 = 8.6%; p = 0.350), but not effect on HbA1c (WMD = − 0.72%; 95% CI: − 1.85 to 0.40; p = 0.209; I2 = 92.7%; p < 0.001).”
    Quoted verbatim from The effect of barberry supplementation on components of metabolic syndrome: a grade assessment systematic review and meta-analysis of randomized controlled trials..
    Study
    meta-analysis
    Dose
    75 mg/day to 10 g/day fruit or supplement; 200 to 480 mL/day juice; 3 to 12 weeks
    Population
    Adults in randomized trials (T2DM, NAFLD, metabolic syndrome, benign breast disease, hypertension), all conducted in Iran; trials pooled barberry fruit/powder supplement and barberry juice against placebo or control

    Effect -0.72 mean difference, 95% CI -1.85 to 0.4

    The effect of barberry supplementation on components of metabolic syndrome: a grade assessment systematic review and meta-analysis of randomized controlled trials.2025PMID:4088602810.1186/s41043-025-01067-yPermalink

To cite this finding: https://catalystproject.ai/e/01M5MZQQB1876PRGXVMNEDMBHC

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