Cu(2+)/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Cu(2+) — increases all-cause mortality
Evidence strength: limited.Findingreplicated ×1“In multivariable Cox regression adjusting for demographic and clinical covariates (Model-3), HCLs ≥ 50 µg/g was associated with an 18.5-fold increased hazard of all-cause mortality (HR = 18.51; p = 0.032).”
Quoted verbatim from Hepatic Copper Accumulation Predicts Fibrosis Progression and Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).. - Study
- cohort
- Population
- Adults with biopsy-proven MASLD, high (>= 50 ug/g dry tissue) versus normal (< 50 ug/g) hepatic copper on liver biopsy; endogenous hepatic copper, nobody dosed
Effect 18.51 hazard ratio
Hepatic Copper Accumulation Predicts Fibrosis Progression and Mortality in Patients with Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD).2025PMID:4101044910.3390/nu17182923Permalink
To cite this finding: https://catalystproject.ai/e/01M5MYENYBNE4PFJ21S143GSQF