α-tocopherol/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
α-tocopherol — no detected effect on all-cause mortality
Evidence strength: moderate.FindingNull resultreplicated ×4“In addition, there was no significant effect of vitamin E on total mortality (HR, 1.08; 95% CI, 0.98–1.19; P=0.13) or cancer mortality (HR, 1.13; 95% CI, 0.95–1.34; P=0.16).”
Quoted verbatim from Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial.. - Study
- RCT
- Dose
- 400 IU synthetic alpha-tocopherol on alternate days
- Population
- 14,641 male US physicians aged 50 or older; 2x2x2x2 factorial, with vitamin C, multivitamin and beta carotene randomised independently; mean follow-up 8.0 years
Effect 1.08 hazard ratio, 95% CI 0.98 to 1.19
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial.2009PMID:1906636810.1001/jama.2008.862Industry fundedPermalink
To cite this finding: https://catalystproject.ai/e/01M5MXBCHNA9796PKN4ADQ2YNH