α-tocopherol/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
α-tocopherol — no detected effect on colorectal cancer incidence
Evidence strength: moderate.FindingNull resultreplicated ×2“We found no effect for any site-specific cancers, including colorectal (HR, 0.88; 95% CI, 0.64–1.19; P=0.40), lung (HR, 0.89; 95% CI, 0.60–1.31; P= 0.55), bladder (HR, 1.21; 95% CI, 0.76–1.94; P=0.43), and pancreatic (HR, 1.14; 95% CI, 0.67–1.93; P=0.63) cancer.”
Quoted verbatim from Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial.. - Study
- RCT
- Dose
- 400 IU synthetic alpha-tocopherol on alternate days
- Population
- 14,641 male US physicians aged 50 or older; 2x2x2x2 factorial, with vitamin C, multivitamin and beta carotene randomised independently
Effect 0.88 hazard ratio, 95% CI 0.64 to 1.19
Vitamins E and C in the prevention of prostate and total cancer in men: the Physicians' Health Study II randomized controlled trial.2009PMID:1906636810.1001/jama.2008.862Industry fundedPermalink
To cite this finding: https://catalystproject.ai/e/01M5MXBA9DGN9E4HKY8C31SP45