α-tocopherol/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
α-tocopherol — increases prostate cancer incidence
Evidence strength: limited.Finding“The rate of prostate cancer detection was greater in all treatment groups when compared with placebo but was statistically significant only in the vitamin E alone group (HR 1.17, 99% CI 1.004-1.36, p=0.008) (Table 3).”
Quoted verbatim from Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).. - Study
- RCT
- Dose
- 400 IU/day all rac-alpha-tocopheryl acetate, planned follow-up 7 to 12 years
- Population
- Healthy men aged 50 or older (black men) or 55 or older (others), PSA 4 ng/mL or less, in the four-arm SELECT trial; vitamin E alone arm (with selenium placebo) against placebo plus placebo; extended follow-up through July 2011
Effect 1.17 hazard ratio, 95% CI 1.004 to 1.36
Vitamin E and the risk of prostate cancer: the Selenium and Vitamin E Cancer Prevention Trial (SELECT).2011PMID:2199029810.1001/jama.2011.1437Industry fundedPermalink
To cite this finding: https://catalystproject.ai/e/01M5MWQB4B38B6QADQTXFTARJC