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α-tocopherol/Finding

One finding, on its own

A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.

  • α-tocopherol — no detected effect on urinary bladder cancer incidence

    Evidence strength: moderate.FindingNull resultreplicated ×1
    “The bladder cancer rate was higher in the 3 treatment arms than in the placebo arm but no difference was statistically significant (vitamin E HR 1.06, 99% CI 0.72 – 1.53, selenium HR 1.13, 99% CI 0.78–1.63, vitamin E plus selenium HR 1.05, 99% CI 0.71 – 1.51).”
    Quoted verbatim from Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT..
    Study
    RCT
    Dose
    400 IU daily all-rac-alpha-tocopheryl acetate
    Population
    Men aged 50 or older (55 or older if not black) without prior prostate cancer in SELECT; vitamin E alone arm vs placebo, 2x2 factorial with selenium; secondary analysis

    Effect 1.06 hazard ratio, 95% CI 0.72 to 1.53

    Evaluation of vitamin E and selenium supplementation for the prevention of bladder cancer in SWOG coordinated SELECT.2012PMID:2249822010.1016/j.juro.2012.01.117Permalink

To cite this finding: https://catalystproject.ai/e/01M5MW1TJCN93TRDZ6FFN6EH8Z

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