metformin/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
metformin — decreases all-cause mortality
Evidence strength: moderate.Findingreplicated ×1“The results of the meta-analysis with a random-effects model showed that septic patients who received metformin prior to hospitalization had significantly lower mortality compared to those without metformin use (OR, 0.58; 95% CI, 0.44–0.75, P < 0.00001).”
Quoted verbatim from Association of preadmission metformin use and prognosis in patients with sepsis with diabetes: a systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Adults with diabetes admitted with sepsis; pooled observational cohort studies comparing preadmission metformin users with non-users; mortality horizons pooled across studies (28-day, 30-day, 60-day, 90-day, 365-day, ICU and in-hospital)
Effect 0.58 odds ratio, 95% CI 0.44 to 0.75
Association of preadmission metformin use and prognosis in patients with sepsis with diabetes: a systematic review and meta-analysis.2026PMID:4208787310.3389/fendo.2026.1815219Permalink
To cite this finding: https://catalystproject.ai/e/01M5JD6E8D3CNG2RPE7GXBYYH2