ethanol/Finding
One finding, on its own
A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Increases alanine aminotransferase
InsufficientEvidence strength: insufficient. Mechanistic inference, no evidence found, or evidence weakened below very limited.Finding“Chronic ethanol consumption resulted in significant increases in plasma alanine aminotransferase in MF (1.84-fold) and HF mice (2.33-fold), yet liver triglycerides only increased significantly in the HF model (1.62-fold).”
Quoted verbatim from Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis.. - Study
- animal · not in humans
- Duration
- 6 weeks
- Dose
- ethanol 2%-6% in modified Lieber-DeCarli liquid diet, increasing concentrations, 6 weeks
- Population
- Male C57BL/6J mice pair-fed a modified Lieber-DeCarli diet with moderate fat or high fat calories, with ethanol versus the same diet without ethanol
Increased dietary fat contributes to dysregulation of the LKB1/AMPK pathway and increased damage in a mouse model of early-stage ethanol-mediated steatosis.2013PMID:23465594Permalink
Keep reading
- Everything the graph holds on ethanol
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To cite this finding: https://catalystproject.ai/e/01M4PKY70E3MFCB2NS0Z21SH53