magnesium(2+)/Finding
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Decreases hamilton Depression Rating Scale (HDRS) total score
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“The reduction in HDRS total score was greater in the intervention group than in the control group (-6.35 vs -2.80, p < 0.001), particularly in the domains of mood and insomnia.”
Quoted verbatim from Magnesium supplementation as an adjunct to fluoxetine therapy for depression.. - Study
- RCT
- Duration
- 6 weeks
- Dose
- magnesium 250 mg/day oral, adjunct to fluoxetine 20 mg/day
- Population
- adults aged 18-45 with new-onset or chronic depression, all receiving background fluoxetine 20 mg/day
Magnesium supplementation as an adjunct to fluoxetine therapy for depression.2026PMID:41916937Permalink
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- Everything the graph holds on magnesium(2+)
- Every compound studied against Hamilton Depression Rating Scale (HDRS) total score
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To cite this finding: https://catalystproject.ai/e/01M2R89XTEH9M5RS64957MSN1T