melatonin/Finding
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A single claim from the graph, with the evidence strength computed from its study, the sentence it was drawn from, and the paper. This address does not change.
Decreases incidence of postoperative delirium
Very limitedEvidence strength: very limited. Human evidence with major recorded weaknesses, or non-human, uncontrolled or unverified evidence.Finding“Melatonin administered less than 5 elimination half-lives before the surgery significantly reduced the POD incidence (OR = 0.31, 95% CI 0.19-0.49, P < .00001).”
Quoted verbatim from Melatonin and its analogues for the prevention of postoperative delirium: A systematic review and meta-analysis.. - Study
- meta-analysis
- Population
- Adult surgical patients; subgroup pooled analysis (6 RCTs, 2 cohort studies, 1 case-control study) restricted to melatonin administered less than 5 elimination half-lives before surgery
Effect 0.31 odds ratio, 95% CI 0.19 to 0.49
Melatonin and its analogues for the prevention of postoperative delirium: A systematic review and meta-analysis.2020PMID:32145098Permalink
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- Everything the graph holds on melatonin
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To cite this finding: https://catalystproject.ai/e/01M1W4AFNV5S22W1QM9TW8F6YZ