familial vesicoureteral reflux
Findings
No curated finding names familial vesicoureteral reflux yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Familial vesicoureteral reflux is a rare, non-syndromic urogenital tract malformation characterized by the familial occurrence of retrograde flow of urine from the bladder into the ureter and sometimes the kidneys. Patients may be asymptomatic or may present with recurrent, sometimes febrile, urinary tract infections that, in case of acute pyelonephritis, may lead to serious complications (renal scarring, hypertension, renal failure). Spontaneous resolution of the disorder is possible.
Definition from the Mondo Disease Ontology (MONDO:0017329), read 2026-09-29. CC BY 4.0.
Genes
3 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
Other names
2 names
Resolves to: familial vesicoureteral reflux
- Also called
- familial VURhereditary vesicoureteral reflux (disease)