vesicoureteral reflux 2
MONDO:0012573Mondo
Findings
No curated finding names vesicoureteral reflux 2 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any vesicoureteral reflux in which the cause of the disease is a mutation in the ROBO2 gene.
Definition from the Mondo Disease Ontology (MONDO:0012573), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
2 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Renal hypoplasiaHPOHP:0000089
- Vesicoureteral refluxHPOHP:0000076
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- ROBO2HGNC:10250
- Strong · Ambry Genetics · Autosomal dominant · 2018
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2021
- Strong · PanelApp Australia · Autosomal dominant · 2025
Where it sits
- A kind of
Other names
3 names
Resolves to: vesicoureteral reflux 2
- Also called
- ROBO2 vesicoureteral reflux (disease)vesicoureteral reflux (disease) caused by mutation in ROBO2vesicoureteral reflux type 2