vesicoureteral reflux 8
MONDO:0014422Mondo
Findings
No curated finding names vesicoureteral reflux 8 yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any vesicoureteral reflux in which the cause of the disease is a mutation in the TNXB gene.
Definition from the Mondo Disease Ontology (MONDO:0014422), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance
HPO, annotations 2026-09-02
Features
4 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Joint hypermobilityHPOHP:0001382
- 2 of 2 reported patients
- Recurrent urinary tract infectionsHPOHP:0000010
- 8 of 8 reported patients
- Duplicated collecting systemHPOHP:0000081
- 5 of 9 reported patients
- Vesicoureteral refluxHPOHP:0000076
- 5 of 9 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- TNXBHGNC:11976
- Limited · Labcorp Genetics (formerly Invitae) · Autosomal dominant · 2017
Where it sits
- A kind of
Other names
3 names
Resolves to: vesicoureteral reflux 8
- Also called
- TNXB vesicoureteral reflux (disease)vesicoureteral reflux (disease) caused by mutation in TNXBvesicoureteral reflux type 8