early-onset non-syndromic cataract
Findings
No curated finding names early-onset non-syndromic cataract yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Early-onset non-syndromic cataract is a rare, genetic, non-syndromic developmental defect of the eye, with high clinical and genetic heterogeneity, most frequently characterized by bilateral, symmetrical, non-progressive cataracts which present at birth or in early-childhood. Additional ocular manifestations (e.g. anterior segment dysgenesis, colobomas, nystagmus, microcornea, microphthalmia, myopia) may be associated, however other organs/systems are usually not affected.
Definition from the Mondo Disease Ontology (MONDO:0011060), read 2026-09-29. CC BY 4.0.
Genes
3 genes
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
Where it sits
- A kind of
- Narrower terms (29)
- cataract 10 multiple types
- cataract 11 multiple types
- cataract 13 with adult I phenotype
- cataract 14 multiple types
- cataract 15 multiple types
- cataract 17 multiple types
- cataract 19 multiple types
- cataract 20 multiple types
- cataract 21 multiple types
- cataract 22 multiple types
- cataract 23
- cataract 26 multiple types
- cataract 31 multiple types
- cataract 32 multiple types
- cataract 33
- cataract 38
- cataract 39 multiple types
- cataract 40
- cataract 42
- cataract 43
- cataract 44
- cataract 45
- cataract 46 juvenile-onset
- cataract 5 multiple types