cataract 19 multiple types
Findings
No curated finding names cataract 19 multiple types yet. Everything below is reference data from Mondo, HPO and GenCC, not evidence about what affects it.
Definition
Any early-onset non-syndromic cataract in which the cause of the disease is a mutation in the LIM2 gene.
Definition from the Mondo Disease Ontology (MONDO:0014111), read 2026-09-29. CC BY 4.0.
- Inheritance
- Autosomal dominant inheritance · Autosomal recessive inheritance
- Onset and course
- Congenital onset · Late onset · Infantile onset · Middle age onset · Juvenile onset · Childhood onset
HPO, annotations 2026-09-02
Features
21 features
What the disease is reported to present with, and how often among people who have it — never how often a feature means the disease. HPO, annotations 2026-09-02.
- Abnormal optic disc morphologyHPOHP:0012795
- 11 of 11 reported patients
- AmblyopiaHPOHP:0000646
- 4 of 4 reported patients
- Blurred visionHPOHP:0000622
- 3 of 3 reported patients
- CataractHPOHP:0000518
- 10 of 10 reported patients
- Cortical pulverulent cataractHPOHP:0007780
- 7 of 7 reported patients
- ExotropiaHPOHP:0000577
- 8 of 8 reported patients
- GlaucomaHPOHP:0000501
Show the remaining 9
- Lamellar cataractHPOHP:0007971
- 2 of 5 reported patients
- Posterior polar cataractHPOHP:0001115
- 2 of 5 reported patients
- Alternating esotropiaHPOHP:0001137
- 1 of 3 reported patients
- Pulverulent cataractHPOHP:0010693
- 5 of 17 reported patients
- Nuclear cataractHPOHP:0100018
- 4 of 14 reported patients
- Chorioretinal atrophyHPOHP:0000533
- 3 of 11 reported patients
Genes
1 gene
Germline variants in the gene encoding each protein, as classified by GenCC submitters, each in their own words. Limited, disputed and refuted submissions are listed too.
- LIM2HGNC:6610
- Definitive · G2P · Autosomal recessive · 2017
- Strong · Labcorp Genetics (formerly Invitae) · Autosomal recessive · 2020
- Strong · PanelApp Australia · Autosomal dominant · 2025
- Strong · PanelApp Australia · Autosomal recessive · 2025
- Limited · Ambry Genetics · Autosomal recessive · 2022
Where it sits
- A kind of
Other names
4 names
Resolves to: cataract 19 multiple types
- Also called
- cataract type 19CTRCT19early-onset non-syndromic cataract caused by mutation in LIM2LIM2 early-onset non-syndromic cataract