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Proteins/UNIPROT:Q13515

BFSP2

Protein·UNIPROT:Q13515

Open in the graph

Required for the correct formation of lens intermediate filaments as part of a complex composed of BFSP1, BFSP2 and CRYAA. Plays a role in maintenance of retinal lens optical clarity (By similarity)..

Function from UniProtKB (Q13515), read 2026-09-23. CC BY 4.0.

Curated compounds routed: 0

What the reference databases state

Inferred

Inferred — not reported by a source. Evidence key

GenCC submitters' classifications

5 rows

cataract 12 multiple types has a germline basis in BFSP2DiseaseGenCC HGNC:1041|MONDO:0012701Inferred only
early-onset lamellar cataract has a germline basis in BFSP2DiseaseGenCC HGNC:1041|MONDO:0018611Inferred only
early-onset non-syndromic cataract has a germline basis in BFSP2DiseaseGenCC HGNC:1041|MONDO:0011060Inferred only
early-onset sutural cataract has a germline basis in BFSP2DiseaseGenCC HGNC:1041|MONDO:0020372Inferred only
pulverulent cataract has a germline basis in BFSP2DiseaseGenCC HGNC:1041|MONDO:0011430Inferred only

Statements

5 statements

5 statements · 1 reference database · Subject: BFSP2 · Sources: Hetionet

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ARHGAP40 covaries with BFSP2ProteinHetionet hetionet:covaries:343578-8419Inferred only
CDX1 covaries with BFSP2ProteinHetionet hetionet:covaries:1044-8419Inferred only
CRTC1 covaries with BFSP2ProteinHetionet hetionet:covaries:23373-8419Inferred only
BFSP2 covaries with OTUD7AProteinHetionet hetionet:covaries:161725-8419Inferred only
BFSP1 interacts with BFSP2ProteinHetionet hetionet:interacts:631-8419Inferred only

Other names

8 names

Resolves to: BFSP2

Also called: 49 kDa cytoskeletal proteinBeaded filament structural protein 2CP47CP49Lens fiber cell beaded filament protein CP 47Lens fiber cell beaded filament protein CP 49Lens intermediate filament-like lightLIFL-L

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