Compound

L-gulonate

The L-enantiomer of gulonate.

Definition from ChEBI (CHEBI:13115), read 2026-09-23. CC BY 4.0.

CHEBI:13115ChEBI

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Structure

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A generated conformer of L-gulonate — one low-energy arrangement PubChem computed, not a measured structure. Hydrogens are not drawn; the formula counts them.

Class: Organic compound, anion
Formula: C6H11O7
Mass: 195.147 g/mol
Charge: -1
InChIKey: RGHNJXZEOKUKBD-QTBDOELSSA-M
SMILES: O=C([O-])[C@@H](O)[C@@H](O)[C@H](O)[C@@H](O)CO
Look it up: ChEBI PubChem By InChIKey

Identity from ChEBI, geometry from PubChem. Not evidence.

What it touches on the way

Mechanistic reach

4 entities

4 entities reached.

0 reported hops4 assembled from the scaffold

What the reference databases state

Statements

14 statements

14 statements · 2 reference databases · Subject: L-gulonate · Sources: Human-GEM, Rhea

Order

L-gulonate is converted to 3-dehydro-L-gulonateCompoundRhea RHEA:12889Inferred only
L-gulonate is converted to 3-dehydro-L-gulonateCompoundHuman-GEM MAR08352Inferred only
3-dehydro-L-gulonate is converted to L-gulonateCompoundHuman-GEM MAR08352Inferred only
L-gulonate is converted to L-gulono-1,4-lactoneCompoundRhea RHEA:42516Inferred only
L-gulono-1,4-lactone is converted to L-gulonateCompoundHuman-GEM MAR08346Inferred only
L-gulono-1,4-lactone is converted to L-gulonateCompoundRhea RHEA:42516Inferred only
L-gulonate is converted to L-gulono-1,4-lactoneCompoundHuman-GEM MAR08346Inferred only
L-gulonate is a substrate of AKR1A1ProteinHuman-GEM MAR06537Inferred only
L-gulonate is a substrate of AKR1A1ProteinRhea RHEA:14909Inferred only
L-gulonate is a substrate of AKR1A1ProteinHuman-GEM MAR08344Inferred only
L-gulonate is a substrate of AKR1B1ProteinRhea RHEA:14909Inferred only
L-gulonate is a substrate of CRYL1ProteinHuman-GEM MAR08352Inferred only

Show the remaining 2

L-gulonate is a substrate of CRYL1ProteinRhea RHEA:12889Inferred only
L-gulonate is a substrate of RGNProteinHuman-GEM MAR08346Inferred only

Reactions

9 reactions

MAM01973c+proton+NADPH(4-)L-gulonate+NADP(3-)
Catalysed by AKR1A1
Reaction pageReversibleBalancedEC 1.1.1.2cytosol
Human-GEM MAR06537CC BY 4.0Reference data
MAM01973r+proton+NADPH(4-)L-gulonate+NADP(3-)
Catalysed by AKR1A1
Reaction pageReversibleBalancedEC 1.1.1.19, 1.1.1.2endoplasmic reticulum
Human-GEM MAR08344CC BY 4.0Reference data
water+L-gulono-1,4-lactoneproton+L-gulonate
Catalysed by RGN
Reaction pageReversibleBalancedEC 3.1.1.17endoplasmic reticulum
Human-GEM MAR08346CC BY 4.0Reference data
L-gulonateL-gulonate
Reaction pageLeft to rightBalancedendoplasmic reticulum, cytosol
Human-GEM MAR08351CC BY 4.0Reference data
3-dehydro-L-gulonate+proton+NADH(2-)L-gulonate+NAD(+)
Catalysed by CRYL1
Reaction pageReversibleBalancedEC 1.1.1.45cytosol
Human-GEM MAR08352CC BY 4.0Reference data
L-gulonate+NAD(1-)3-dehydro-L-gulonate+NADH(2-)+hydron
Catalysed by CRYL1
Reaction pageLeft to rightBalanced
Rhea RHEA:12889CC BY 4.0Reference data
L-gulonate+NADP(3-)CHEBI:142686+NADPH(4-)+hydron
Catalysed by AKR1A1 or AKR1B1
Reaction pageDirection not assertedBalanced
Rhea RHEA:14909CC BY 4.0Reference data
L-gulono-1,4-lactone+waterL-gulonate+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:42516CC BY 4.0Reference data
L-gulonate+NAD(1-)CHEBI:59881+NADH(2-)+hydron
Reaction pageDirection not assertedBalanced
Rhea RHEA:43496CC BY 4.0Reference data

Other names

1 name

Resolves to: L-gulonate

Also called: Gulonate