Skip to content

Reference

Evidence

CompoundsSubstances with curated findings
OutcomesMeasured endpoints
ProteinsTransporters and enzymes
InteractionsPairs that share biology
PapersEvery paper a finding cites
ArticlesReadings of the evidence

Reference layer

PathwaysReactions grouped under one name
ProcessesWhat proteins are annotated as doing
AnatomyTissues, by what is expressed there
Cell typesCells, by what is expressed there
OrganismsSpecies a compound is prepared from
MaterialsSubstances that are not one molecule
AssessmentsRegulatory determinations, transcribed

Atlas Graph Access

Search the graph

Atlas Graph Access Compounds Outcomes Proteins Interactions Papers Articles Pathways Processes Anatomy Cell types Organisms Materials Assessments

Loading the page.

Catalyst

The evidence graph for human biochemistry. Every edge carries its source, its study design, and a grade computed from both.

The graph

Compounds
Outcomes
Proteins
Atlas
Interactions
Papers
Articles
Graph
Search

Reference layer

Pathways
Processes
Anatomy
Cell types
Organisms
Materials
Assessments

How it works

Mission
Method
How to read the evidence
Sources and licences

Build on it

Access
For agents
Query the graph
Bulk export

A reference for what the literature reports. Not medical advice.

© 2026 CatalystPrivacy TermsReference data under the licences listed on the attribution page.

Compound

3alpha-hydroxy-5beta-androstan-17-one

CHEBI:28195ChEBI

Open in the graph

What it touches on the way

Inferred

Not reported; assembled from reference reactions.

Mechanistic reach

3 entities

3 entities reached.

0 reported hops3 assembled from the scaffold

UGT1A1ProteinUNIPROT:P22309metabolized byInferred only25 paths25 endpoints
UGT1A10ProteinUNIPROT:Q9HAW8metabolized byInferred only14 paths14 endpoints
UGT1A8ProteinUNIPROT:Q9HAW9metabolized byInferred only11 paths11 endpoints

What the reference databases state

Statements

4 statements

4 statements · 1 reference database · Subject: 3alpha-hydroxy-5beta-androstan-17-one · Sources: Human-GEM

Search this listOrder

3alpha-hydroxy-5beta-androstan-17-one is converted to 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)CompoundHuman-GEM MAR07980Inferred only
3alpha-hydroxy-5beta-androstan-17-one is metabolised by UGT1A1ProteinHuman-GEM MAR07980Inferred only
3alpha-hydroxy-5beta-androstan-17-one is metabolised by UGT1A10ProteinHuman-GEM MAR07980Inferred only
3alpha-hydroxy-5beta-androstan-17-one is metabolised by UGT1A8ProteinHuman-GEM MAR07980Inferred only

Reactions

7 reactions

3alpha-hydroxy-5beta-androstan-17-one+UDP-alpha-D-glucuronate3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+UDP
Catalysed by UGT1A1 or UGT1A8 or UGT1A10
Reaction pageLeft to rightBalancedEC 2.4.1.17GO:0005783
Human-GEM MAR07980CC BY 4.0Reference data
3alpha-hydroxy-5beta-androstan-17-one3alpha-hydroxy-5beta-androstan-17-one
Reaction pageReversibleBalancedGO:0005829, GO:0005783
Human-GEM MAR09177CC BY 4.0Reference data
3alpha-hydroxy-5beta-androstan-17-one3alpha-hydroxy-5beta-androstan-17-one
Reaction pageReversibleBalancedGO:0005829, GO:0005615
Human-GEM MAR09178CC BY 4.0Reference data
3alpha-hydroxy-5beta-androstan-17-one
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09453CC BY 4.0Reference data
ATP+3alpha-hydroxy-5beta-androstan-17-one+waterADP+3alpha-hydroxy-5beta-androstan-17-one+proton+phosphate(3-)
Transported by ABCB1
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR11759CC BY 4.0Reference data
ATP+3alpha-hydroxy-5beta-androstan-17-one+waterADP+3alpha-hydroxy-5beta-androstan-17-one+proton+phosphate(3-)
Reaction pageLeft to rightBalancedGO:0005829, GO:0005783
Human-GEM MAR11853CC BY 4.0Reference data
3alpha-hydroxy-5beta-androstan-17-one+NAD(1-)5beta-androstane-3,17-dione+NADH(2-)+hydron
Reaction pageDirection not assertedBalance undeterminable
Rhea RHEA:10356CC BY 4.0Reference data