Compound
3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)
A steroid glucuronide anion that is the conjugate base of etiocholan-3α-ol-17-one 3-O-(β-D-glucuronide) arising from deprotonation of the carboxylic group; major species at pH 7.3.
Definition from ChEBI (CHEBI:178197), read 2026-09-23. CC BY 4.0.
Structure
Loading the model…
- Class
- Organic compound, anion
- Formula
- C25H37O8
- Mass
- 465.563 g/mol
- Charge
- -1
- InChIKey
- VFUIRAVTUVCQTF-SDHZCXLISA-M
- SMILES
- [H][C@]12CC[C@]3([H])[C@]([H])(CC[C@]4(C)C(=O)CC[C@@]34[H])[C@@]1(C)CC[C@@H](O[C@@H]1O[C@H](C(=O)[O-])[C@@H](O)[C@H](O)[C@H]1O)C2
- Look it up
- ChEBIPubChemBy InChIKey
Identity from ChEBI, geometry from PubChem. Not evidence.
What it touches on the way
Mechanistic reach
2 entities
2 entities reached.
0 reported hops2 assembled from the scaffold
What the reference databases state
Statements
3 statements
3 statements · 2 reference databases · Subject: 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) · Sources: Human-GEM, Rhea
- 3alpha-hydroxy-5beta-androstan-17-one is converted to 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)CompoundHuman-GEM MAR07980Inferred only
- 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) is a substrate of CHST10ProteinRhea RHEA:68704Inferred only
- 3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate) is transported by ABCC1ProteinHuman-GEM MAR07982Inferred only
Reactions
6 reactions
3alpha-hydroxy-5beta-androstan-17-one+UDP-alpha-D-glucuronate3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+UDP
Catalysed by UGT1A1 or UGT1A8 or UGT1A10
Reaction pageLeft to rightBalancedEC 2.4.1.17GO:0005783
Human-GEM MAR07980CC BY 4.0Reference data
3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)
Reaction pageReversibleBalancedGO:0005829, GO:0005783
Human-GEM MAR07981CC BY 4.0Reference data
ATP+3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+waterADP+3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+proton+phosphate(3-)
Transported by ABCC1
Reaction pageLeft to rightBalancedGO:0005829, GO:0005615
Human-GEM MAR07982CC BY 4.0Reference data
3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)
Reaction pageReversibleBalance undeterminableGO:0005615
Human-GEM MAR09257CC BY 4.0Reference data
3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+3'-phosphoadenylyl sulfate3alpha-hydroxyetiocholan-17-one 3-O-(3-sulfo-beta-D-glucuronate)+adenosine 3',5'-bisphosphate+hydron
Catalysed by CHST10
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:68704CC BY 4.0Reference data
3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+ATP(4-)+water3alpha-hydroxyetiocholan-17-one 3-O-(beta-D-glucuronate)+ADP(3-)+hydrogenphosphate+hydron
Transported by ABCC2
Reaction pageLeft to rightBalance undeterminable
Rhea RHEA:86843CC BY 4.0Reference data