What it touches on the way
Mechanistic reach
21 entities
21 entities reached.
0 reported hops21 assembled from the scaffold
- GSTP1ProteinUNIPROT:P09211metabolized byInferred only141 paths36 endpoints
- GSTA2ProteinUNIPROT:P09210metabolized byInferred only92 paths23 endpoints
- GSTM4ProteinUNIPROT:Q03013metabolized byInferred only86 paths26 endpoints
- GSTA1ProteinUNIPROT:P08263metabolized byInferred only78 paths21 endpoints
- GSTO1ProteinUNIPROT:P78417metabolized byInferred only64 paths16 endpoints
- MGST1ProteinUNIPROT:P10620substrate ofInferred only60 paths15 endpoints
- GSTA3ProteinUNIPROT:Q16772metabolized byInferred only56 paths14 endpoints
- GSTM1ProteinUNIPROT:P09488metabolized byInferred only52 paths13 endpoints
- MGST3ProteinUNIPROT:O14880substrate ofInferred only44 paths11 endpoints
- HPGDSProteinUNIPROT:O60760substrate ofInferred only44 paths11 endpoints
- MGST2ProteinUNIPROT:Q99735substrate ofInferred only40 paths10 endpoints
- PTGESProteinUNIPROT:O14684substrate ofInferred only39 paths13 endpoints
Show the remaining 9
- GSTZ1ProteinUNIPROT:O43708metabolized byInferred only36 paths9 endpoints
- GSTM5ProteinUNIPROT:P46439metabolized byInferred only36 paths9 endpoints
- GSTA5ProteinUNIPROT:Q7RTV2metabolized byInferred only36 paths9 endpoints
- GSTO2ProteinUNIPROT:Q9H4Y5metabolized byInferred only36 paths9 endpoints
- GSTT2BProteinUNIPROT:P0CG30metabolized byInferred only24 paths6 endpoints
- GSTM3ProteinUNIPROT:P21266metabolized byInferred only20 paths5 endpoints
- GSTM2ProteinUNIPROT:P28161metabolized byInferred only16 paths4 endpoints
- GSTK1ProteinUNIPROT:Q9Y2Q3metabolized byInferred only8 paths2 endpoints
- GSTA4ProteinUNIPROT:O15217metabolized byInferred only4 paths1 endpoint
What the reference databases state
Statements
83 statements
83 statements · 1 reference database · Subject: 12-oxo-leukotriene B4 · Sources: Human-GEM
- 12-oxo-leukotriene B4 is metabolised by GSTA1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA2ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA2ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA2ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA2ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA3ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA3ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA3ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA3ProteinHuman-GEM MAR01119Inferred only
Show the remaining 71
- 12-oxo-leukotriene B4 is metabolised by GSTA4ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA4ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA4ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA4ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA5ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA5ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA5ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTA5ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTK1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTK1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTK1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTK1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM2ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM2ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM2ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM2ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM3ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM3ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM3ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM3ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM4ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM4ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM4ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM4ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM5ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM5ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM5ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTM5ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO2ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO2ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO2ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTO2ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTP1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTP1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTP1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTP1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTT2BProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTT2BProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTT2BProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTT2BProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTZ1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTZ1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTZ1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is metabolised by GSTZ1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of HPGDSProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of HPGDSProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is a substrate of HPGDSProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is a substrate of HPGDSProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST1ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST1ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST1ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST1ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST2ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST2ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST2ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST2ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST3ProteinHuman-GEM MAR01119Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST3ProteinHuman-GEM MAR01121Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST3ProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of MGST3ProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is a substrate of PTGESProteinHuman-GEM MAR01122Inferred only
- 12-oxo-leukotriene B4 is a substrate of PTGESProteinHuman-GEM MAR01120Inferred only
- 12-oxo-leukotriene B4 is a substrate of PTGESProteinHuman-GEM MAR01121Inferred only
Reactions
17 reactions
MAM02364c+NAD(+)12-oxo-leukotriene B4+proton+NADH(2-)
Catalysed by DHRS4 or CBR1 or CBR3
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005829
Human-GEM MAR01100CC BY 4.0Reference data
MAM02364m+NAD(+)12-oxo-leukotriene B4+proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005759
Human-GEM MAR01101CC BY 4.0Reference data
MAM02364m+NADP(3-)12-oxo-leukotriene B4+proton+NADPH(4-)
Catalysed by DHRS4 or CBR1 or CBR3
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005759
Human-GEM MAR01102CC BY 4.0Reference data
MAM02364r+NAD(+)12-oxo-leukotriene B4+proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005783
Human-GEM MAR01103CC BY 4.0Reference data
MAM02364x+NADP(3-)12-oxo-leukotriene B4+proton+NADPH(4-)
Catalysed by DHRS4 or CBR1 or CBR3
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005777
Human-GEM MAR01105CC BY 4.0Reference data
MAM02364x+NAD(+)12-oxo-leukotriene B4+proton+NADH(2-)
Reaction pageLeft to rightBalancedEC 1.1.1.184GO:0005777
Human-GEM MAR01106CC BY 4.0Reference data
12-oxo-leukotriene B4+proton+NADPH(4-)+dioxygenMAM00331c+water+NADP(3-)
Catalysed by CYP4F11 or CYP4F22 or CYP4F2 or CYP4F8 or CYP4F3
Reaction pageLeft to rightBalancedEC 1.14.14.94GO:0005829
Human-GEM MAR01107CC BY 4.0Reference data
12-oxo-leukotriene B4+proton+NADPH(4-)+dioxygenMAM00331r+water+NADP(3-)
Catalysed by CYP4F11 or CYP4F22 or CYP4F2 or CYP4F8 or CYP4F3
Reaction pageLeft to rightBalancedEC 1.14.14.94GO:0005783
Human-GEM MAR01108CC BY 4.0Reference data
12-oxo-leukotriene B4+CHEBI:16856MAM00333c
Catalysed by MGST1 or GSTO2 or GSTP1 or MGST2 or GSTZ1 or GSTT2B or GSTM1 or GSTM5 or GSTM3 or MGST3 or GSTO1 or HPGDS and 8 more alternatives
Reaction pageReversibleBalancedEC 2.5.1.18GO:0005829
Human-GEM MAR01119CC BY 4.0Reference data
12-oxo-leukotriene B4+CHEBI:16856MAM00333m
Catalysed by MGST1 or GSTO2 or GSTP1 or MGST2 or GSTZ1 or GSTT2B or GSTM1 or GSTM5 or GSTM3 or MGST3 or PTGES or GSTO1 and 9 more alternatives
Reaction pageReversibleBalancedEC 2.5.1.18GO:0005759
Human-GEM MAR01120CC BY 4.0Reference data
12-oxo-leukotriene B4+CHEBI:16856MAM00333r
Catalysed by MGST1 or GSTO2 or GSTP1 or MGST2 or GSTZ1 or GSTT2B or GSTM1 or GSTM5 or GSTM3 or MGST3 or PTGES or GSTO1 and 9 more alternatives
Reaction pageReversibleBalancedEC 2.5.1.18GO:0005783
Human-GEM MAR01121CC BY 4.0Reference data
12-oxo-leukotriene B4+CHEBI:16856MAM00333x
Catalysed by MGST1 or GSTO2 or GSTP1 or MGST2 or GSTZ1 or GSTT2B or GSTM1 or GSTM5 or GSTM3 or MGST3 or PTGES or GSTO1 and 9 more alternatives
Reaction pageReversibleBalancedEC 2.5.1.18GO:0005777
Human-GEM MAR01122CC BY 4.0Reference data