PapersPMID:42961639
Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial.
What moved
1 findingHow to read these marks →- Increases left ventricular ejection fraction
very limited
“At 30 days, the NAD⁺ group demonstrated a modest but significant improvement in LVEF compared with the placebo group (56.32 ± 8.04% vs. 53.37 ± 8.12%, p = 0.048).”
- Study
- RCT
- Duration
- 7 days
- Dose studied
- intravenous NAD+ 10 mg/day for 7 days
- Population
- Patients with ST-segment elevation myocardial infarction undergoing primary PCI, all receiving standard medical therapy; LVEF at 30 days
Study record
- Design
- randomised controlled trial
- Species
- human
- Population
- Patients with STEMI undergoing primary PCI; intravenous NAD+ 10 mg/day versus placebo for 7 days, both in addition to standard medical therapy (balanced background)
- Participants
- 120
- Comparator
- placebo
- Duration
- not reported
- Endpoints measured
- 4