NAD(+) increases left ventricular ejection fraction (imaging modality unspecified)

raisesVery limited evidenceFinding

01 · The sentence it was drawn from

“At 30 days, the NAD⁺ group demonstrated a modest but significant improvement in LVEF compared with the placebo group (56.32 ± 8.04% vs. 53.37 ± 8.12%, p = 0.048).”

Quoted verbatim from Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial.

This finding among the 1 finding on its endpoint

NAD(+)

Left ventricular ejection fraction (imaging modality unspecified)

raises

Who: Patients with ST-segment elevation myocardial infarction undergoing primary PCI, all receiving standard medical therapy; LVEF at 30 days
Dose studied: intravenous NAD+ 10 mg/day for 7 days

Very limited evidencePMID 42961639 · 2026

02 · The study

Study: RCT
Duration: 7 days

Evidence, by strength

strong
moderate
limited
very limitedthis finding
insufficient

03 · The paper

American journal of cardiovascular drugs

Effect of Intravenous Nicotinamide Adenine Dinucleotide on Left Ventricular Function After Primary Percutaneous Coronary Intervention in ST-Segment Elevation Myocardial Infarction: A Randomized Controlled Trial.

2026PMID 42961639doi 10.1007/s40256-026-00826-4

What else it reported1 finding · 1 compound · 1 endpoint

04 · To cite this finding

This address does not change

https://catalystproject.ai/e/01M7034VB7RD6CR999X6JBQE8T